Plant Transcription Factor Database
Previous version: v3.0
Picea abies
WOX Family
Species TF ID Description
MA_9427942g0010WOX family protein
MA_33318g0010WOX family protein
MA_121643g0010WOX family protein
MA_74653g0010WOX family protein
MA_8832398g0010WOX family protein
MA_1910g0010WOX family protein
MA_747816g0010WOX family protein
MA_8850184g0010WOX family protein
MA_10344604g0010WOX family protein
MA_124915g0010WOX family protein
MA_59896g0010WOX family protein
MA_129591g0010WOX family protein
MA_42637g0010WOX family protein
MA_116716g0010WOX family protein
MA_10432361g0010WOX family protein
MA_161092g0010WOX family protein
MA_8044496g0010WOX family protein
MA_10234279g0010WOX family protein
MA_128969g0010WOX family protein
WOX Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401

The WOX genes form a plant-specific subclade of the eukaryotic homeobox transcription factor superfamily, which is characterized by the presence of a conserved DNA-binding homeodomain. The analysis of WOX gene expression and function shows that WOX family members fulfill specialized functions in key developmental processes in plants, such as embryonic patterning, stem-cell maintenance and organ formation. These functions can be related to either promotion of cell division activity and/or prevention of premature cell differentiation.

van der Graaff E, Laux T, Rensing SA.
The WUS homeobox-containing (WOX) protein family.
Genome Biol, 2009. 10(12): p. 248.
PMID: 20067590